What is guaifenesin and phenylephrine?

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The medicines below all contain the following active ingredient(s): guaifenesin + phenylephrine. You can select a medicine from this list to find out more - including side effects, age restrictions, food interactions and whether the medicine is subsidised by the government on the pharmaceutical benefits scheme (PBS).

Medicines that contain guaifenesin + phenylephrine

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Home Knowledge Center Wellness Library guaifenesin and phenylephrine

What is the most important information I should know about guaifenesin and phenylephrine? What is guaifenesin and phenylephrine? What should I discuss with my healthcare provider before taking guaifenesin and phenylephrine? How should I take guaifenesin and phenylephrine? What happens if I miss a dose? What happens if I overdose? What should I avoid while taking guaifenesin and phenylephrine? What are the possible side effects of guaifenesin and phenylephrine? What other drugs will affect guaifenesin and phenylephrine? Where can I get more information?

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ACETAMINOPHEN; GUAIFENESIN; PHENYLEPHRINE (a set a MEE noe fen; gwye FEN e sin; fen il EF rin) is a combination of a pain reliever, expectorant and decongestant. It is used to treat fever, aches and pains, and congestion from a cold or the flu. It is also used to treat a dry cough. This medicine will not treat an infection.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): Duratuss A, Mucinex Fast-Max, Mucinex Fast-Max Congestion & Headache, Mucinex Sinus-Max, Sudafed PE Head Congestion + Mucus, Sudafed PE Pressure + Pain + Mucus, Sudafed PE Triple Action, Tylenol Cold Head Congestion Severe, Tylenol Sinus, Tylenol Sinus Congestions & Pain Severe Daytime, Tylenol Sinus Severe Congestion

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

How should I use this medication?

Take this medicine by mouth with a full glass of water. Follow the directions on the label. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with any of the following medications:

This medicine may also interact with the following medications:

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your doctor or health care professional if your pain symptoms do not start to get better or if they get worse.

Drink several glasses of water each day. This will help loosen mucus.

Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.

Do not take more than the recommended dose as listed on the package label. If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.

The risk for liver problems is increased if you drink 3 or more drinks containing alcohol daily while using this product.

Side effects that you should report to your doctor or health care professional as soon as possible:

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

This medicine may cause accidental overdose and death if taken by other adults, children, or pets. Mix any unused medicine with a substance like cat littler or coffee grounds. Then throw the medicine away in a sealed container like a sealed bag or a coffee can with a lid. Do not use the medicine after the expiration date.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2022 Cerner Multum, Inc. Version: 13.09. Revision date: 1/26/2017.

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