Molecules and moles are important to understand when studying chemistry and physical science. Here's an explanation of what these terms mean, how they relate to Avogadro's number, and how to use them to find molecular and formula weight. Show
A molecule is a combination of two or more atoms that are held together by chemical bonds, such as covalent bonds and ionic bonds. A molecule is the smallest unit of a compound that still displays the properties associated with that compound. Molecules may contain two atoms of the same element, such as O2 and H2, or they may consist of two or more different atoms, such as CCl4 and H2O. A chemical species consisting of a single atom or ion is not a molecule. So, for example, an H atom is not a molecule, while H2 and HCl are molecules. In the study of chemistry, molecules are usually discussed in terms of their molecular weights and moles. A related term is a compound. In chemistry, a compound is a molecule consisting of at least two different types of atoms. All compounds are molecules, but not all molecules are compounds! Ionic compounds, such as NaCl and KBr, do not form traditional discrete molecules like those formed by covalent bonds. In their solid state, these substances form a three-dimensional array of charged particles. In such a case, molecular weight has no meaning, so the term formula weight is used instead. The molecular weight of a molecule is calculated by adding the atomic weights (in atomic mass units or amu) of the atoms in the molecule. The formula weight of an ionic compound is calculated by adding its atomic weights according to its empirical formula. A mole is defined as the quantity of a substance that has the same number of particles as are found in 12.000 grams of carbon-12. This number, Avogadro's number, is 6.022x1023. Avogadro's number may be applied to atoms, ions, molecules, compounds, elephants, desks, or any object. It's just a convenient number to define a mole, which makes it easier for chemists to work with very large numbers of items. The mass in grams of one mole of a compound is equal to the molecular weight of the compound in atomic mass units. One mole of a compound contains 6.022x1023 molecules of the compound. The mass of one mole of a compound is called its molar weight or molar mass. The units for molar weight or molar mass are grams per mole. Here is the formula for determining the number of moles of a sample: mol = weight of sample (g) / molar weight (g/mol) Converting between molecules and moles is done by either multiplying by or dividing by Avogadro's number:
For example, if you know there are 3.35 x 1022 water molecules in a gram of water and want to find how many moles of water this is: moles of water = molecules of water / Avogadro's number moles of water = 3.35 x 1022 / 6.02 x 1023 moles of water = 0.556 x 10-1 or 0.056 moles in 1 gram of water Key Concepts⚛ 1 mole of any substance contains 6.022 × 1023 particles. ⚛ 6.022 × 1023 is known as the Avogadro Number or Avogadro Constant and is given the symbol NA(1) ⚛ N = n × NA · N = number of particles in the substance · n = amount of substance in moles (mol) · NA = Avogardro Number = 6.022 × 1023 particles mol-1 N = n × (6.022 × 1023) ⚛ To calculate the number of particles, N, in a substance: N = n × NA N = n × (6.022 × 1023) ⚛ To calculate the amount of substance in moles, n : n = N ÷ NA n = N ÷ (6.022 × 1023) Please do not block ads on this website. Deriving and Applying the Equation N = n × NA1 mole of a pure substance contains NA particles, or 6.022 × 1023 particles. Imagine a box containing 1 mole of helium gas, He(g), represented in the diagram on the right as an X
Imagine we now add another mole of helium gas, He(g), also represented in the diagram on the right as an X
The number of helium atoms (N) in the box is equal to the moles of helium atoms (n) multiplied by the Avogadro number (NA): N = n × NA We can use this mathematical equation (mathematical formula or mathematical expression) to find the number of particles (N) in any amount of substance (n) just by multiplying the amount in moles (n) by the Avogadro number (NA) as shown in the table below:
The mathematical equation, N = n × NA, can be used to find the number of atoms, ions or molecules in any amount (in moles) of atoms, ions or molecules:
The mathematical equation, N = n × NA, can also be used to find the number of atoms of each element in a known amount (in moles) of a compound. For a compound with the molecular formula XaYb: ⚛ 1 molecule of compound XaYb contains a atoms of element X b atoms of element Y ⚛ 1 mole of compound XaYb contains a moles of atoms of element X b moles of atoms of element Y ⚛ n moles of compound XaYb contains (n × a) moles of atoms of element X (n × b) moles of atoms of element Y ⚛ n moles of compound XaYb contains (n × a) × NA atoms of element X (n × b) × NA atoms of element Y ⚛ n moles of compound XaYb contains (n × a) × 6.022 × 1023 atoms of element X (n × b) × 6.022 × 1023 atoms of element Y Consider n moles of each of these compounds with the general formula XY2. The table below gives the moles of each element present in the compound, and also shows us how to calculate the number of atoms of each element present:
If we have 5 moles of each the compounds above, for example, then we can calculate the moles of each element, and the number of atoms of each element as shown in the table below:
↪ Back to top Deriving and Applying the Equation n = N ÷ NA (n=N/NA)In the previous section we derived the mathematical equation: N = n × NA where: N = the number of particles present in the substance n = the amount of particles in the substance in moles (mol) NA = Avogadro number = 6.022 × 1023 particles mol-1 If we divide both sides of this equation by NA as shown below: We arrive at the equation shown below: which we can use to find the moles of substance if we know how many particles of the substance are present. The equation n=N/NA or n = N ÷ NA can be used to calculate:
The table below shows the calculation of moles (n) given then number of particles (N):
If you know a substance contains 3.011 × 1023 particles of the substance, then the moles of substance will be (3.011 × 1023) ÷ (6.022 × 1023) = 0.5 mol 3.011 × 1023 helium atoms = 0.5 mol of helium atoms 3.011 × 1023 sodium ions = 0.5 mol of sodium ions 3.011 × 1023 water molecules = 0.5 mol of water molecules The equation n = N ÷ NA can also be used to find the amount in moles of atoms or ions in a compound if you know both the molecular formula for the compound and the number of molecules of the compound that are present. For N molecules of a compound with the general formula XaYb: number of atoms of element X = N(X) = N × a number of atoms of element Y = N(Y) = N × b moles of atoms of element X = n(X) = (N × a) ÷ NA moles of atoms of element Y = n(Y) = (N × b) ÷ NA Consider the following examples in which 1.927 × 1024 molecules of a compound with the general formula X2Y are present
↪ Back to top Worked Examples: Moles-Avogadro Number CalculationsThe solutions to these problems are given as a set of 6 general steps to help structure your approach to problem solving:
Calculating the number of particles (N = n × NA)Question 1: Calculate the number of ammonia, NH3, molecules in 3.5 moles of ammonia. Solution: Step 1: What is the question asking you to do? Calculate the number of ammonia molecules. N(ammonia) = number of ammonia molecules = ? Step 2: What information (data) has been given in the question? molecular formula for ammonia: NH3 n = amount of ammonia molecules in moles = 3.5 mol Step 3: What is the relationship between the moles of particles and the number of particles? N = n × NA where N = number of particles n = moles of particles NA = Avogadro number = 6.022 × 1023 Step 4: Write the equation for the relationship between between moles of ammonia molecules and number of ammonia molecules: N(NH3) = n(NH3) × NA N(NH3) = n(NH3) × (6.022 x 1023) Step 5: Substitute in the vales and solve for N: N(NH3) = 3.5 × (6.022 × 1023) N(NH3) = 2.1 × 1024 ammonia (NH3) molecules (Note: 2 significant figures are justified) Step 6: Write the answer number of ammonia molecules = 2.1 × 1024 molecules Question 2. Determine the number of hydrogen atoms in 1.5 moles of water, H2O, molecules. Solution: Step 1: What is the question asking you to do? Calculate the number of hydrogen atoms. N(H atoms) = number of hydrogen atoms = ? Step 2: What information (data) has been given in the question? molecular formula for water: H2O n(H2O molecules) = moles of water molecules = 1.5 mol Step 3: What is the relationship between moles of particles and number of particles? N = n × NA where N = number of particles n = moles of particles NA = Avogadro number = 6.022 × 1023 Step 4: What is the relationship between moles of water molecules and number of hydrogen atoms? (i) relationship between moles of water molecules and number of water molecules is: N(H2O molecules) = n(H2O molecules) × NA where N(H2O molecules) = 1.5 × (6.022 × 1023) = 9.033 × 1023 (ii) relationship between number of hydrogen atoms and number of water molecules: From the molecular formula we see that 1 molecule of water is made up of 2 atoms of hydrogen and 1 atom of oxygen. N(H atoms) = 2 × N(H2O molecules) Step 5: Substitute in the values and solve the equation: N(H atoms) = 2 × N(H2O molecules) N(H atoms) = 2 × (9.033 × 1023) N(H atoms) = 1.8 × 1024 hydrogen atoms (Note: 2 significant figures are justified) Step 6: Write the answer number of hydrogen atoms = 1.8 × 1024 hydrogen atoms Calculating the moles of substance (n=N/NA)Question 1. A sample of gas contains 4.4 × 1024 carbon dioxide molecules. Solution: Step 1: What is the question asking you to do? Calculate the moles of carbon dioxide molecules. n(carbon dioxide molecules) = moles of carbon dioxide molecules = ? mol Step 2: What information (data) has been given in the question? N(carbon dioxide molecules) = number of carbon dioxide molecules N(carbon dioxide molecules) = 4.4 × 1024 carbon dioxide molecules Step 3: What is the relationship between moles (n) of particles and number (N) of particles? n = N ÷ NA Step 4: What is the relationship between moles (n) of carbon dioxide molecules and number (N) of carbon dioxide molecules? n(carbon dioxide molecules) = N(carbon dioxide molecules) ÷ NA n(carbon dioxide molecules) = N(carbon dioxide molecules) ÷ (6.022 × 1023) Step 5: Substitute the values into the equation and solve: n(carbon dioxide molecules) = N(carbon dioxide molecules) ÷ (6.022 × 1023) n(carbon dioxide molecules) = (4.4 × 1024) ÷ (6.022 × 1023) n(carbon dioxide molecules) = 7.3 moles of carbon dioxide molecules (Note: 2 significant figures are justified) Step 6: Write the answer moles of carbon dioxide molecules = 7.3 mol Question 2. A sample contains 2.4 × 1022 molecules of oxygen gas (O2). Solution: Step 1: What is the question asking you to do? Calculate the moles of oxygen atoms. n(O atoms) = moles of oxygen atoms = ? mol Step 2: What information (data) has been given in the question? molecular formula for oxygen gas: O2 N(O2 molecules) = number of oxygen molecules (O2) = 2.4 × 1022 Step 3: What is the relationship between moles (n) of particles and number (N) of particles? n = N ÷ NA Step 4: What is the relationship between moles of oxygen atoms, n(O atoms), and number of oxygen molecules, N(O2 molecules)? (i) relationship between moles of oxygen atoms, n(O atoms), and number of oxygen atoms, N(O atoms) n(O atoms) = N(O atoms) ÷ NA (ii) relationship between number of oxygen molecules, N(O2 molecules), and number of oxygen atoms, N(O atoms): One O2 molecule is made up of 2 oxygen atoms number of oxygen atoms = 2 × number of oxygen molecules N(O atoms) = 2 × N(O2 molecules) (iii) relationship between moles of oxygen atoms, n(O atoms), and number of oxygen molecules, N(O2 molecules):
Step 5: Substitute in the values and solve the equation:
(Note: 2 significant figures are justified) Step 6: Write the answer moles of oxygen atoms = 0.080 mol ↪ Back to top Problem Solving: Moles, Number of Particles, and Avogadro Number The Problem: Bo the Biologist has been studying the effect of chloride ions, Cl-, on plant cells. Bo has asked Chris the Chemist to make 1 litre of a solution containing 0.50 moles of chloride ions, Cl-, dissolved in water. The solution must also contain equal numbers of sodium ions, Na+, and potassium ions, K+. Chris makes the solution by dissolving some sodium chloride, NaCl, and potassium chloride, KCl, in 1 litre of de-ionised water. Solving the Problem using the StoPGoPS model for problem solving:
1.5 × 1023 sodium ions in the solution ↪ Back to top Sample Question: Moles, Number of Particles and Avogadro's NumberWhich of the following pure substances contains the lowest number of oxygen atoms? Back to top
Footnotes: (1) The Avogadro number is sometimes referred to as Loschmidt's number and is given the symbol L. ↪ Back to top |