Which of the following best supports the claim that binding of miRNA miRNA Delta to the miRNA miRNA binding site inhibits translation of gene Q mRNA mRNA?

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Page 2

From: MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-19

hsa-miRNA	Potential interest related to SARS-CoV-2 infection
miR-16	Abundant in A549 cells, suppresses viral replication in EV71 infection, regulation of apoptosis [58]
miR-29	Abundant in A549 cells
miR-30	Abundant in A549 cells, upregulated in RSV exosomes [59]
miR-186	Indirect regulation of HIV-1 infection [60]
miR-130	Downregulated in HCV infection [40]
miR-27	Abundant in A549 cells, role in MCMV and HCV infection [40]
miR-595	Repressed in RSV infected A549 cells [61]
miR-182	Upregulated in RSV exosomes [59], miR-183 cluster regulation of innate antiviral response [32]
miR-199	Proviral functions in HCV infection [46]
miR-20	Abundant in A549 cells
miR-93	Potential target site in VSV genome [40]
miR-218	Role in NF-κB signaling pathway [46]
miR-23	Abundant in A549 cells, upregulated in RSV exosomes [59]
miR-203	Upregulated IAV infection, inhibits viral replication [62]
miR-320	Upregulated in HCV infection, proviral functions [46], upregulated in RSV exosomes [59]
miR-135	Role in immune response [63]
miR-19	Role in type I interferon signaling pathway, antiviral effects [46], upregulated in RSV exosomes [59]
miR-122	Role in type I interferon signaling pathway, antiviral effects [46]
miR-520	Role in immune response [62], induced in RSV infected A549 cells [61]
miR-21	Abundant in A549 cells, NF-κB signaling pathway [46], upregulated in RSV exosomes [59]
miR-26	Role in immune response [63]
miR-125	Abundant in A549 cells, regulation of apoptosis [46]
miR-92	Abundant in A549 cells
miR-155	Role in type I interferon signaling pathway, antiviral effects [46]
miR-183	miR-183 cluster regulation of innate antiviral response [32]
miR-224	Tumor suppressive functions [64]
miR-200	Upregulated in H5N1 infection, targets the 3′-UTR of ACE2 [65]
miR-24	Upregulated in RSV exosomes [59], abundant in A549 cells, antiviral in IAV and RSV infection [35]
miR-198	Repressed in RSV infected A549 cells [61]
let-7	Abundant in A549 cells, involved in NF-κB signaling and inflammation [46]
miR-223	Downregulated in RSV exosomes [58], role in SARS-CoV infection [48]
miR-98	Role in immune response [62], role in SARS-CoV infection [48]
miR-337	Induced in RSV infected A549 cells [61]
miR-146	Role in NF-κB signaling pathway, proviral functions [46], downregulated in RSV exosomes [59]
miR-185	Regulation of host metabolic pathways and HCV infection [28]
miR-744	Antiviral functions against RSV and influenza viruses [46]
miR-192	Abundant in A549 cells
miR-127	Upregulated in M2 macrophages, downregulated by inflammation [64]
miR-187	Anti-inflammatory effects [64]

Human (hsa) miRNAs that were identified to be highly abundant in lung epithelial A549 cells and/or to have roles in metabolism, the immune response, or other viral infections are presented. miRNAs are listed in decreasing order of the total number of binding sites predicted in the SARS-CoV-2 genome
ACE angiotensin-converting enzyme, EV71 enterovirus 71, H5N1 highly pathogenic Asian avian influenza A virus, HCV hepatitis C virus, HIV-1 human immunodeficiency virus 1, IAV influenza A virus, MCMV murine cytomegalovirus, miRNA/miR- microRNA, RSV respiratory syncytial virus, SARS-CoV severe acute respiratory syndrome coronavirus, SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, UTR untranslated region, VSV vesicular stomatitis virus