How long does second shot symptoms last

Like all medicines, vaccines can cause side effects. It’s normal to experience side effects after the vaccine. It shows the vaccine is teaching your body’s immune system how to protect itself from the disease. Not everyone gets side effects. Most side effects are mild and normally last only a day or two.

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Side effects of the coronavirus (COVID-19) vaccination

Very common side effects in the first day or two include:

  • having a painful, heavy feeling and tenderness in the arm where you had your injection
  • feeling tired
  • headache, aches and chills
  • diarrhoea, nausea and vomiting
  • mild flu-like symptoms

These common side effects are much less serious than developing coronavirus or complications associated with coronavirus. They usually go away within a few days.

If you feel uncomfortable, you can rest and take paracetamol. Make sure you take paracetamol as directed on the label or leaflet. Remember, do not take medicines that contain aspirin if you're under 16 years of age.

If your side effects seem to get worse or if you're concerned, phone NHS 24 free on 111. Tell them about your vaccination so that they can assess you properly.

Fever after the coronavirus vaccine

It’s quite common to develop a fever (temperature above 37.8C) after a vaccination. This normally happens within 48 hours of the vaccination and usually goes away within 48 hours. This is an expected reaction.

If the fever starts more than 48 hours after the vaccination, or lasts longer than 48 hours, you should seek medical advice as you may have coronavirus or another infection.

Side effects for each dose

Not all coronavirus vaccines are the same. Some tend to cause more side effects after the first dose, others cause more side effects after additional doses. The very common side effects are the same and should still only last a day or two.

Even if you do have side effects after the vaccine, NHS Scotland advises you get all recommended doses. The full recommended course will give you the best protection against the virus.

Waiting time after your coronavirus vaccination

As long as you feel ok, you should only stay for 5 minutes after your coronavirus vaccination.

Make sure you tell the vaccination staff if you have:

  • a history of allergies, particularly to other vaccines
  • had an immediate reaction after your previous doses
  • previously fainted following vaccination

In these circumstances, you may be advised to stay for 15 minutes. A family history of allergies (or even anaphylaxis) is not a risk factor.

You must not drive for 15 minutes after the vaccine because of the risk of fainting.

If you experience symptoms of an allergic reaction, call out for help and/or phone 999 immediately (or ask someone to do this for you). Symptoms usually happen within 15 minutes of vaccination.

You should look out for the following allergic symptoms:

  • persistent cough
  • vocal changes (hoarse voice)
  • swollen tongue causing difficulty swallowing
  • difficult or noisy breathing
  • wheezing (like an asthma attack)
  • feeling lightheaded or prolonged faint
  • clammy skin
  • confusion
  • unresponsive or unconscious

Less common side effects

Swollen glands in the armpit or neck

An uncommon side effect is swollen glands in the armpit or neck, on the same side as the arm where you had the vaccine. This can last for around 10 days. If it lasts longer, speak to your health professional.

If you are due for breast screening (a mammogram) then you should mention that you have had the vaccine when you attend.

Heart inflammation

Worldwide, there have also been recent, rare cases of inflammation of the heart called myocarditis or pericarditis reported after coronavirus vaccines. However, it's not yet clear that these are caused by the vaccines.

Most of these cases have been in younger men and usually happen a few days after vaccination. Most of these people recovered and felt better following rest and simple treatments. Longer term follow-up is ongoing in the UK and elsewhere to better understand this reaction.

You should seek medical advice urgently if you experience:

  • chest pain
  • shortness of breath
  • feelings of having a fast-beating, fluttering, or pounding heart

Getting your second Covid-19 vaccine: what you need to know

How long does second shot symptoms last
Updated 16 September 2022

We answer all the questions you may have about your second dose of the Covid-19 vaccine, from when to book your second dose to common side effects.

What's on this page

When to have your second dose

  • Why do I need to have two doses of the vaccine?
  • How long after my first dose should I have my second dose?
  • Can I have my second dose earlier than eight weeks?
  • What should I do if I missed my second dose appointment?
  • What happens if I don’t get the second jab within 12 weeks?
  • How long does the second dose take to become effective?
  • Should I get a second dose if I feel unwell?
  • If I get coronavirus after my first dose, should I delay my second dose?

What are the risks and side effects of the second dose?

  • AstraZeneca: what are the side effects of the second dose?
  • How long do side effects last from the second dose of the Oxford/AstraZeneca vaccine?
  • Pfizer: what are the side effects of the second dose?
  • How long do side effects last from the second dose of the Pfizer vaccine?
  • Moderna: what are the side effects of the second dose?
  • How long do side effects last from the second dose of the Moderna vaccine?
  • Does the second dose have the same risks as the first?
  • What’s the risk of getting a blood clot after my second dose of the AstraZeneca vaccine?
  • Is myocarditis more common after a second dose of the vaccine?

How to book or change your appointment

  • How do I move my second dose forward?
  • How do I book my second appointment for the coronavirus vaccine?
  • When will I be contacted to book my second appointment?
  • What do I do if there are no appointments available?
  • What do I do if my local vaccine centre or GP is no longer offering appointments?

Questions about your second dose appointment

  • What if I’m pregnant or under 40? Can I choose which vaccine I get as a second dose?
  • Should I have a second dose if I’ve just had surgery?
  • Can I go to a different vaccination centre for my second dose?
  • Do I have to get the second dose in the same arm?
  • Do I need a second dose if I’ve already had the coronavirus?
  • Are there any reasons why I shouldn’t have my second dose?

Looking for information about the booster jab?
Visit our booster page for more information about the booster programme, including when you'll be eligible. 

When to have your second dose

Why do I need to have two doses of the vaccine?

The three vaccines currently available in the UK are all designed to work across two doses. Having two doses leads to a stronger, better immune response from your body and a longer-lasting protection. It is important that everyone gets two doses.

How long after my first dose should I have my second dose?

All adults over the age of 18 (including those with heart and circulatory conditions) are being invited to book their second dose eight weeks after their first dose.

Children aged 12 to 17 will be offered their second dose 12 weeks after their first dose.  

Children aged 5 to 11 will be offered their second dose 8 weeks after their first dose. Each dose will be a third of the adult dose for children in this age group.

We know that having the second dose is essential to ensure the best effect of the vaccine, and to maximise protection against new variants. So it's important to get your second dose as soon as you are offered it.

A large study published in August 2021, but not yet reviewed by other scientists, looked at the effectiveness of the Covid-19 vaccines that have been given in the UK. It found no evidence that there was a difference in effectiveness between a second dose given less than nine weeks from the first dose, compared with more than nine weeks from the first dose.

We’re here for you with information and support around coronavirus

Our fortnightly Heart Matters newsletter includes the latest updates about coronavirus when you have a heart condition, as well as support for healthy eating, staying active and your emotional wellbeing.

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Can I have my second dose earlier than eight weeks?

No, the recommendation from the JCVI is that there is an eight-week gap between your first and second dose – so you won’t be able to book an appointment any sooner than this.

What should I do if I missed my second appointment?

If you missed your appointment, you can make another fmbooking to have your second dose. You can rebook through the NHS booking system if that’s how you booked your first dose, or by phone if you booked your first appointment by phone.

If you know in advance that you can’t attend an appointment, remember to cancel it so that someone else can use your original timeslot.

What happens if I don’t get the second jab within 12 weeks?

It is recommended that you get a second dose within 12 weeks of having the first dose. However, if that isn’t possible for some reason, you should get a second dose as soon as you can to give you better long-term protection against the virus. Depending on how long the delay is, and which vaccine you have, we don’t necessarily have evidence to say whether the delay will affect the level of protection you have. Getting it as soon as you can is the best approach.

How long does the second dose take to become effective?

Generally the second dose of the Covid vaccine, whether Pfizer/BioNTech, Oxford AstraZeneca, or Moderna, will be effective after two weeks. This can vary slightly from person to person, depending on your immune response.

Most studies of the vaccines have measured effectiveness 21 days after the first dose and 14 days after the second dose, and have found significant increases in effectiveness after the second dose.

Some clinical trials of the Pfizer/BioNTech vaccine have found an increase in effectiveness only seven days after the first dose - including a clinical trial of the Pfizer/BioNTech vaccine and a study of the Pfizer-BioNTech vaccine among healthcare workers in England.

Should I get a second dose if I feel unwell?

If you are feeling a little unwell, for example, if you have a cold, there is no medical reason why you can't get the vaccine (as long as you've had a test to make sure it isn't Covid). But if you are able to postpone getting the vaccine until you are recovered that might be more considerate to the people you'll come in contact with when you get the vaccine.

If you are very unwell, for example, if you have a fever, it is recommended that you wait until you are fully recovered to have the second dose.

If I get coronavirus after having my first dose, should I delay my second dose?

If you’ve tested positive for Covid-19, you need to wait before having a second dose of the vaccine.

  • If you're 18 years old or over you should wait 4 weeks (28 days)
  • If you're 12 to 17 years old you should wait 12 weeks (84 days)
  • If you're 12 to 17 years old and at high-risk from Covid-19 you should wait 4 weeks (28 days)

You can rebook through the NHS website or by phone, depending on how you booked your first appointment.

What are the risks and side effects of the second dose?

AstraZeneca: what are the side effects of the second dose?

For the Oxford/AstraZeneca vaccine, side effects tend to be milder with the second dose. The types of side effects are the same and should still only last a day or two. They include pain or discomfort in the arm where you had your injection, headaches, and feeling tired or feverish.

How long do side effects last from the second dose of the Oxford/AstraZeneca vaccine?

Not everyone gets side effects from the Oxford AstraZeneca vaccine. Research has found that side effects from the second dose are less common than from the first dose and are usually gone within a few days. Serious side effects are very rare.

Pfizer: what are the side effects of the second dose?

For the Pfizer/BioNTech vaccine, side effects tend to be stronger with the second dose. The types of side effects are the same and should still only last a day or two. They include pain or discomfort in the arm where you had your injection, headaches, and feeling tired or feverish.

How long do side effects last from the second dose of the Pfizer vaccine?

Not everyone gets side effects from the Pfizer vaccine. Research has found that for those who do experience side effects from the second dose, these are usually gone within one to two days. Serious side effects are very rare.

Moderna: what are the side effects of the second dose?

For the Moderna vaccine, side effects tend to be stronger with the second dose. The types of side effects are the same and should still only last a day or two. They include pain or discomfort in the arm where you had your injection, headaches, and feeling tired or feverish.

How long do side effects last from the second dose of the Moderna vaccine?

Not everyone gets side effects from the Moderna vaccine. Research has found that for those who do experience side effects from the second dose, these last three days on average and are usually gone within four to five days. Serious side effects are very rare.

Does the second dose have the same risks as the first?

You may get relatively minor side effects (chills, headaches, tiredness and pain in your arm) after either the first or second dose. It can vary between individuals and between types of vaccine whether the side effects are more noticeable at first or second dose.

Out of many millions vaccinated, a very small number of people developed a specific type of blood clot in the brain, accompanied with low blood platelet levels, after their first dose of the AstraZeneca vaccine.

There have been an even smaller number of reports of these rare specific types of blood clots in the other two vaccines available in the UK - Pfizer/BioNTech and Moderna.

What’s the risk of getting a blood clot after my second dose of the AstraZeneca vaccine?

Extremely low. Millions of people have now received a second dose of the AstraZeneca vaccine and to date, there have only been a very small number of cases reported of the very rare reaction of a specific type of blood clot in the brain (accompanied with low platelet counts) after a second dose. There have been an even smaller number of reports of these rare specific types of blood clots in the other two vaccines available in the UK - Pfizer/BioNTech and Moderna.

  • Read more about the AstraZeneca vaccine

Is myocarditis more common after a second dose of the vaccine?

In a study in Israel, where most people have Pfizer, fully vaccinated people were about twice as likely to be diagnosed with myocarditis, compared with people who hadn’t had the vaccine. The numbers diagnosed were still very small – 136 out of 5 million people. Another study from Israel found that the risk of developing myocarditis from Covid-19 was far higher than the risk from the vaccine.

  • Read more about Covid-19 vaccines and myocarditis

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How to book or change your appointment

How do I move my second dose forward?

England

If you live in England and your second dose appointment is booked for more than eight week after your first dose, you can rearrange your appointment online or by calling 119.

You will need to cancel your existing appointment to book another slot. It may not be possible to see what other slots are available before you cancel your existing appointment.

Scotland

If you live in Scotland and already have an appointment that is more than 8 weeks after your first dose, you can reschedule online, phone the COVID-19 Vaccination Helpline on 0800 030 8013, or visit a walk-in vaccination clinic eight weeks after your first dose.

Northern Ireland

In Northern Ireland, the Department of Health has announced that eight weeks should be the maximum interval between doses for everyone with vaccine appointments scheduled after 14 June 2021. Depending on where you live and vaccine supply in your area, you may be offered the second dose even sooner.

You can reschedule your appointment online, call 0300 200 7813, or visit a walk-in centre across Northern Ireland.

Wales

In Wales, depending on supply of the vaccine and capacity in your area, you can now reschedule your second dose to be eight weeks from your first dose. You can reschedule your appointment online.

How do I book my second appointment for the coronavirus vaccine?

If you booked your first dose appointment through the NHS coronavirus vaccination website, you should have been able to book an appointment for your second dose at the same time. You can view and change the date of your second appointment through the NHS coronavirus vaccination booking page.

If you booked your first appointment by calling 119, you will be given details of your second appointment over the phone.

If you booked your first appointment through your local GP, pharmacy, or hospital hub, you may have been able to book your second appointment at the same time. If not, you will be contacted by text, by call or by letter closer to the 12-week deadline to make an appointment.

When will I be contacted to book my second appointment?

If you haven’t had a second appointment confirmed yet, you will be contacted nearer the time of the second vaccination date.

What do I do if there are no appointments available?

If there isn’t an appointment available immediately, keep trying through the method you used to book your first dose appointment, or try looking at availability for a different centre.

What do I do if my local vaccine centre or GP is no longer offering appointments?

If the vaccine centre or GP where you had your first dose is no longer offering appointments, you will still be able to book an appointment locally at another venue. 

Questions about your second dose appointment

What if I’m pregnant or under 40? Can I choose which vaccine I get as a second dose?

The government is currently advising pregnant women and healthy people under 40 to get the Moderna or Pfizer/BioNTech instead of the Oxford/AstraZeneca vaccine. But if you have already had the first dose of Oxford/AstraZeneca, you should also have the Oxford/AstraZeneca vaccine as your second dose, even if you are pregnant or under 40.

Should I have a second dose if I’ve just had surgery?

You may be asked to wait a few days (a week at most) after having surgery to have a vaccination. This is so that any reaction you have to the operation can be separated from a reaction to the vaccination.

Can I go to a different vaccination centre for my second dose?

If you book on the NHS coronavirus vaccination website you can choose to go to a different location for your second dose. If you had your first dose through your GP surgery or hospital hub, you can let them know if there is a reason why you need to have your second dose somewhere else. This might be because:

  • You’ve become housebound since your first dose
  • You’ve moved into a care home since your first dose
  • You’ve moved home further away from where you had your first dose

Do I have to get the second dose in the same arm?

No, you can choose which arm you use for your second dose.

Do I need a second dose if I’ve already had the coronavirus?

If you’ve had coronavirus, you have probably developed some natural immunity. But we don’t know how long that immunity lasts. Having two doses of the vaccine is the best way to make sure you have long-lasting and effective protection against the virus.

Are there any reasons why I shouldn’t have my second dose?

Everyone should get a second dose. However, in small number of cases there might be a reason to delay having a second dose. This might be because:

  • You are very unwell, with a fever above 38.5C, and need to wait until you are recovered.
  • Very rarely, someone might have had a serious reaction to their first dose of the vaccine. This is very unusual – the vast majority of people don’t have anything more than minor side effects. This is extremely rare, but if this does apply to you, speak to a healthcare professional about whether your second dose should be a different vaccine.

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Our fortnightly Heart Matters newsletter includes the latest updates about coronavirus when you have a heart condition, as well as support for healthy eating, staying active and your emotional wellbeing.

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How long do side effects last after 2nd injection?

stronger, side effects after your second dose. Most side effects go away in 24-48 hours. sign that you are allergic to any of the vaccine components. who had no side effects AND people who experienced more significant side effects BOTH developed good immunity to the virus in clinical trials.

How long until 2nd shot side effects start?

This vaccine side effect is more common after the second dose, usually occurs within 2 to 4 days after the vaccination, and can last for an average of 10 days.

How long do side effects of Covid last?

People with post-COVID conditions can have a wide range of symptoms that can last more than four weeks or even months after infection. Sometimes the symptoms can even go away or come back again.